Title: Should Prednisone be used in Low Back Pain?
题目：下腰背部疼痛需要用强的松吗？
Author 作者: Michael Bond
翻译：李辉 校对：肖锋

Is there any benefit to the use of prednisone in the treatment of lower back pain? One study showed that about 5% of patients receive prednisone for the treatment of their low back pain, but does it work.
用强的松治疗下腰背部疼痛有好处吗？一项研究显示约5%的患者接受强的松治疗他们的下腰背部疼痛，但它有用吗？
A recent study by Eskin et al published in the Journal of Emergency Medicine looked at this question. They conducted a randomized controlled trial of 18-55 year olds with moderately severe low back. Patients were randomized to receive prednisone 50mg for 5 days or placebo.
最近Eskin等的一项发表在急诊医学杂志上的研究探讨了这个问题。他们对18-55岁中重度腰背部疼痛的患者进行了一项随机对照研究。患者随机接受强的松或安慰剂50mg 共 5天的治疗。
The study enrolled a total of 79 patients, and 12 were lost to follow up. At followup there was no difference in their pain, or in them resuming normal activities, returning to work, or days lost from work. To make matters worse more patients in the prednisone group sought additional medical treatment 40% versus 18%.
这一研究入选了79位患者，12位患者失访。在随访期间，发现在疼痛，恢复正常活动，重返工作，或缺勤天数等没有差异。更糟糕的是，更多强的松组的患者寻求额外的治疗（40% vs. 18%）。
Conclusion: With the results of this study we should continue the treatment of low back pain with non-steroidials, muscle relaxants and exercise. There does not appear to be any role for steroids in the treatment of these patients.
结论：依据这一研究的结果，我们应该继续应用非类固醇类药物，肌肉松弛药物以及锻炼来治疗下腰背部疼痛。类固醇在这些患者的治疗中没有显示出任何作用。
References 参考文献：
Eskin B, Shih RD, Fiesseler FW, et al. Prednisone for emergency department low back pain: a randomized controlled trial. Journal of Emergency Medicine. 2014;47(1):65–70. doi:10.1016/j.jemermed.2014.02.010.