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乙肝的新建议
原作者: Andrea Tenner, 肖锋译 发布日期:2013-08-01

Title: Hepatitis C Recommendations
题目:乙肝的新建议
Author 作者: Andrea Tenner
 
Background 背景资料:
Infection with the Hepatitis C  virus can result in mild to severe liver disease.  Morbidity and mortality from Hep C is increasing the US--many of the 2.7-3.9 million persons with Hep C are not aware of their infection.
丙型肝炎病毒感染可导致轻度到严重的肝脏疾病。丙肝的发病率和死亡率在美国有增加 – 2百7-3百90万的丙肝病人中,许多并不知道自己的感染。
Pertinent Information 相关资料:
- Hepatitis C is now curable for many patients
- 许多丙型肝炎患者现在都可治愈
- Current treatment recommendations are a combination of medications (pegylated interferon plus ribavirin plus a protease inhibitor). 
- 目前的治疗建议是药物综合治疗(聚乙二醇干扰素和利巴韦林和蛋白酶抑制剂)
- Research in this field is very active--treatment is likely to change in the next 3-5 years.
- 在这一领域的研究非常活跃 - 治疗方案很有可能在未来3-5年内改变
- Risk reduction strategies to protect the liver (i.e. eliminating alcohol and Hep A and B vaccination) are also recommended.
- 同时建议应用减少肝脏损害风险战策略(即戒酒和接种甲已肝疫苗)
Critical New Recommendation 关键性的新建议
As much of the disease burden is in the “Baby Boomers,” the CDC  now recommends one time testing of all persons born between 1945 and 1965. 
由于很多疾病都发生在“婴儿潮”人群中,CDC建议所有在1945年和1965年之间出生的人做一次测试。
Bottom Line 底线:
While emergency department management is focused on the treatment of acute complications of liver disease, it is also important to have all age appropriate patients follow-up for testing and treatment of Hepatitis C with their primary care provider.
虽然急诊科治疗的重点是针对肝脏疾病的急性并发症,建议所有适当年龄段的病人与他们的家庭医生进行乙肝的检测和治疗也是相当重要的。
References 参考文献:
Treatment for Hepatitis C Virus Infection in Adults [Internet]. Editors: Chou R, Hartung D, Rahman B, Wasson N, Cottrell E, Fu R.  Rockville (MD): Agency for Healthcare Research and Quality (US); 2012 Nov. Report No.: 12(13)-EHC113-EF.
AHRQ Comparative Effectiveness Reviews.
Recommendations for the identification of chronic hepatitis C virus infection among persons born during 1945-1965. Smith BD, Morgan RL, Beckett GA, Falck-Ytter Y, Holtzman D, Teo CG, Jewett A, Baack B, Rein DB, Patel N, Alter M, Yartel A, Ward JW; Centers for Disease Control and Prevention. MMWR Recomm Rep. 2012 Aug 17;61(RR-4):1-32