原作者： FerminBarrueto，肖锋译 文章来源： 《中华急诊医学杂志》编辑部 发布日期：2013-06-14
Title: DKA Deaths Due to 2nd Generation Antipsychotics
题目：由于第二代抗精神病药导致的DKA致死
Author作者: FerminBarrueto
• Hyperglycemia in the setting of antipsychotic use has been reported mostly with olanzapine (Zyprexa) but does occur with other antipsychotics. A recent study from the NYC medical examiner's office details 17 deaths of DKA due to antipsychotics and found that (from highest to lowest incidence) quetiapine> olanzapine >risperidone were the atypical antipsychotics found with these deaths.
• 服用抗精神病药产生的高血糖多与olanzapine（奥氮平）有关，但也可由其它抗精神病药造成。最近一个来自纽约医学检察官办公室的文章详细报到了17例因抗精神病药导致的死亡，发现这些死亡都与非特异抗精神病药有关，包括（按频率顺序）喹硫平，奥氮平，和利培酮（quetiapine，olanzapine，和risperidone）。
• Remember hyperglycemia occurs with patients on antipsychotics and can lead to hyperglycemia hyperosmolar coma or DKA. Both can be lethal.
• 要记住，服用抗精神病药的病人可出现高血糖，导致高血糖高渗性昏迷或DKA。这两个都可致死。
References参考文献：
Fatal Diabetic Ketoacidosis and Antipsychotic Medication.
Ely SF, Neitzel AR, Gill JR.
J Forensic Sci. 2012 Dec 27. doi: 10.1111/1556-4029.12044.
