Title: Statins in Acute Coronary Syndrome
题目:他汀类药物在急性冠状动脉综合征(ACS)中的应用
Author 作者: Ellen Lemkin
• A recent Cochrane review examined the use of early statin therapy in patients with ACS.
• 近期有一个科可伦文献综述对ACS病人早期应用他汀类药物进行了评估。
• They evaluated 18 studies (14,303 patients), which compared early statin therapy (within 14 days) to placebo or usual care.
• 他们对18个研究报告(14,303个病人)在早期使用他汀类药物(14天内)和安慰剂或常规治疗进行了比较。
• The conclusion was that initiation of early statin therapy does not reduce death, myocardial infarction or stroke up to four months, but reduces the occurrence of unstable angina by 24% at 4 months following ACS.
• 结论是早期应用他汀类药物并没有减少4个月内死亡,心肌梗死或脑卒中发病率,但却使ACS4个月内的不稳定心绞痛减少24%。
• Many smaller studies previously noted benefits with early statin initiation prior to this meta-analysis.
• 在这个研究报告之前,有许多小型的文献报告了早期使用他汀类药物的益处。
References 参考文献:
Statins for acute coronary syndrome. Cochrane Database of Systemic Reviews. Volume 9, 2011.