原作者： Semhar Tewelde，肖锋译 文章来源： 中华急诊医学杂志编辑部 发布日期：2013-04-22
Title: HIV and Coronary Heart Disease (CHD)
题目：艾滋病与冠状动脉心脏病（CHD）
Author 作者: Semhar Tewelde
HIV infected patients are at higher calculated risk for CHD compared w/the general population of the same age
与一般同年龄人相比，艾滋病毒感染者患冠心病的风险性较高
HIV is known to promote atherosclerosis through mechanisms related to immune activation, chronic inflammation, coagulation disorders, and lipid disturbances
艾滋病毒是通过相关的免疫激活，慢性炎症，凝血功能障碍，和血脂紊乱机制，促进动脉粥样硬化形成
Additionally combination anti-retroviral therapy (cART) has an affect on lipid and glucose metabolism demonstrated both in vitro and in vivo
此外，体内和体外试验都证实了联合抗逆转录病毒疗法（cART）对脂质和葡萄糖代谢的影响
The presence of an accelerated process of coronary atherosclerosis in this population is a major concern
这一人群中，冠状动脉粥样硬化进程的加快是一个相当大的问题
Practitioners should have a high index of suspicion when confronted by young HIV patients and further data/strategies to prevent early CHD in HIV-infected patients is warranted
医护人员在治疗年轻的艾滋病患者时应该有一个高度的警觉性，一定要形成一个以防止艾滋病患者发生早期冠心病的方案
References 参考文献：
Boccara F, et al. HIV and Coronary Heart Disease. J Am Coll Cardiol 2013;61:511–23
