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降压治疗有助于心肌梗塞康复
发布日期:2003-08-03
Research by a team from Washington University School of Medicine in St. Louis, the Mayo Clinic in Rochester, Minnesota, the Harvard School of Public Health and several other clinical centers around the United States has found that treating depression and social isolation in recent heart attack patients does not reduce the risk of death or second heart attack.   The results from the Enhancing Recovery in Coronary Heart Disease Patients Study (ENRICHD) are published in the Journal of the American Medical Association.   Social isolation and depression are important risk factors for heart attack and death. About 25 percent of heart attack patients have one of these conditions. The ENRICHD research aimed to lessen risk by ameliorating depression.   "The rates were virtually identical," says Allan S. Jaffe, M.D., a study co-chair and professor of medicine at the Mayo Clinic in Rochester. "Looking at the data retrospectively, it did appear that the risk of death or second heart attack was lower among patients in either group who were taking antidepressant drugs. This finding is intriguing but far from definitive because this study was not set up to test the effects of antidepressant drugs, so the data to be sure about this effect was not available."   Conclusions: "The intervention did not increase event-free survival. The intervention improved depression and social isolation, although the relative improvement in the psychosocial intervention group compared with the usual care group was less than expected due to substantial improvement in usual care patients."